论文部分内容阅读
近年来,急性白血病的治疗取得了很大的进展。尤其是儿童急性淋巴细胞性白血病(ALL),国外报道5年无病生存者占完全缓解病例的50％,亦有达到65～70％,预计其中85％的患儿可基本治愈。这与白血病原发和复发部位(骨髓和中枢神经系统)的侵害逐渐得以解决有关。但睾丸作为第3复发场所,睾丸白血病的发生率正在上升,应视为本病早期复发和致死的重要原因之一。本文就其临床表现、诊治、预防及对生育的影响等,综述如下。
In recent years, the treatment of acute leukemia has made great progress. Especially children with acute lymphoblastic leukemia (ALL), foreign reports of 5-year disease-free survival accounted for 50% of complete remission cases, also reached 65 to 70%, 85% of the estimated 85% of children can be basically cured. This is related to the gradual resolution of the infiltration of the primary and relapsed parts of leukemia (bone marrow and central nervous system). However, the testis as the third place of recurrence, the incidence of testicular leukemia is rising, should be considered as one of the important causes of early recurrence and death of the disease. This article on its clinical manifestations, diagnosis and treatment, prevention and impact on fertility, summarized as follows.