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不育控制既可直接降低害鼠种群的生育率,又能影响个体的社会行为,引起种群内等级关系和社群结构的变化,进而干扰种群繁殖。为探究不同剂量卡麦角林对雄鼠行为的影响和持效时间,选取健康雄性黄毛鼠使用50μg/kg和100μg/kg卡麦角林灌胃给药,并于给药后第1 d和第18 d与正常雄鼠遭遇,第4 d和第21 d与正常雌鼠遭遇,比较给药前(卡麦角林灌胃前4 d和前1 d时分别与正常雄鼠和雌鼠遭遇)和给药后个体行为的差异。结果显示:卡麦角林降低了雄鼠对正常雄鼠的探究、攻击时间,降低雄鼠对正常雌鼠的攻击时间和频次;100μg/kg卡麦角林降低雄鼠对正常雌鼠的探究频次,且雄鼠自身修饰和休息频次显著减少。这表明卡麦角林可干扰黄毛鼠对同性和异性个体间的社会行为。此外,药物处理后第18 d和第21 d,雄性个体与同性和异性个体的社会行为与处理前无显著差异,表明停药后药物对行为的影响会随着时间的延长逐渐消失。
Infertility control can directly reduce the fertility rate of pest population, but also affect the social behavior of individuals, causing changes in the hierarchical relationship and community structure within the population, thus interfering with population reproduction. In order to explore the effects of different doses of cabergoline on the behavior of male rats and their duration of action, healthy male rhesus rats were orally administered with cabergoline at doses of 50μg / kg and 100μg / kg, On the 18th day, the mice were exposed to normal male rats. The mice were exposed to normal females on the 4th and 21st days. Before administration (compared with the normal males and females respectively before 4 and 1 day before administration of cabergoline) Differences in individual behavior after administration. The results showed that cabergoline reduced the male rats' inquisition and attack time to the normal male rats, reduced the attack time and frequency of the male rats on the normal female rats, reduced the probing frequency of male mice to the normal female rats by 100μg / kg cabergoline, And males self-modification and rest frequency significantly reduced. This suggests that cabergoline may interfere with the social behavior of rhesus rats for same-sex and opposite-sex individuals. In addition, there was no significant difference between the male and the same-sex and heterosexual individuals on the 18th day and the 21st day after drug treatment, indicating that the influence of the drug on the behavior will gradually disappear with the passage of time after drug withdrawal.