论文部分内容阅读
食管癌发病率的地区聚集性早有报道。已知南非的食管癌发病率最高,其次是苏联、伊朗和我国北方与南方某些地区。食管癌发生的部位,约1/2发生在食管的中段,其余发生在食管的上段与下段。食管癌的前驱因子,可能与食管炎,食管本身功能减退,缺铁性咽下困难或称Plummer-Vmson二氏综合征,以及一些化学药物对食管的损伤或鱼类之骨刺刺伤食管表面粘膜久而久之改变了食管基因,为癌细胞之增生与发展创造了条件,所有这些因子不能不与食管癌之发生无关,但其关系是否十分密切不能一概而论。
Regional aggregation of esophageal cancer incidence has long been reported. South Africa is known to have the highest incidence of esophageal cancer, followed by the Soviet Union, Iran and parts of northern and southern China. Esophageal cancer occurs in about 1/2 occurred in the middle of the esophagus, the rest occurred in the upper and lower esophagus. Esophageal cancer precursors, may be associated with esophagitis, esophageal dysfunction, dysphagia or iron deficiency dyspepsia, or Plummer-Vmson’s syndrome, and some chemical drugs on the esophagus or fish bone spurs wound on the surface of the esophageal mucosa Over time, the esophageal gene has been changed, creating conditions for the proliferation and development of cancer cells. All of these factors can not but have nothing to do with the occurrence of esophageal cancer, but whether the relationship is very close can not be generalized.