论文部分内容阅读
蛔虫移行期幼虫可引起严重的病理过程,损害肺、脾、肝和其他器官系统。为此,作者观察了抗线虫药物对小鼠体内猪蛔虫移行期幼虫的作用。实验用体重12～16克的小鼠,每只鼠经口感染猪蛔虫卵800±100个。在感染后第2～5天给动物进行治疗4天。共实验了14种抗线虫药物,每天用药剂量相当于LD_(50)的1/20,总剂量为1/5LD_(50)。第1组实验动物于感染后第7天(幼虫在肺期)解剖,将肺组织磨碎,在0.7%胃液中消化24小时,在
Roundworms migratory larvae can cause serious pathological processes, damage to lungs, spleen, liver and other organ systems. To this end, the authors observed the effect of anti-nematode drugs on swarm larvae of Ascaris suum in mice. Experimental mice weighing 12 to 16 grams were challenged with 800 ± 100 swine Ascaris suum orally in each mouse. The animals were treated for 4 days 2 to 5 days after infection. A total of 14 kinds of anti-nematode drugs were tested, the daily dose equivalent to LD_ (50) 1/20, the total dose of 1 / 5LD_ (50). Group 1 experimental animals were dissected on day 7 post-infection (larvae in the lung stage), the lung tissue was grated, digested in 0.7% gastric juice for 24 hours,