A convenient synthesis of pyrroles catalyzed by acidic resin under solvent-free condition

来源 :Chinese Chemical Letters | 被引量 : 0次 | 上传用户:pstolyb
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A convenient and effective Paal-Knorr condensations of 2,5-hexanedione with most amines have been carried out at room temperature under solvent-free condition.Macroporous strongly acidic styrol resin(D001) as a novel,efficient,cost-effective,and reusable solid acid catalyst for the synthesis of pyrroles under the same conditions.The pyrroles were obtained in high yields in short reaction times. A convenient and effective Paal-Knorr Condensations of 2,5-hexanedione with most amines have been carried out at room temperature under solvent-free conditions. Macroporous strongly acidic styrol resin (D001) as a novel, efficient, cost-effective, and reusable solid acid catalyst for the synthesis of pyrroles under the same conditions. pyrroles were obtained in high yields in short reaction times.
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