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The fact that most men are severely distressed by pharmaceutical and/ or surgical treatments resulting in functional castrations is inherently obvious.Unfortunately,significant male infertility,predictable after some types of treatment,is often not considered or discussed with patients.rnAs Wibowo et al.1 discussed in their chapter,differences in how medical conditions affecting fertility are accepted are markedly different between diseases of“eldedy men” versus those conditions found while men are in their 20s or 30s.Age-based variability in counseling is inherent in multiple disease states.