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肝炎是输血疗法最常见的并发症。作者于1978年10月至1981年8月,在西班牙对心脏手术施行体外循环的307例病人进行了输血后肝炎发病率的前瞻性调查。62例因各种原因而淘汰,15例在手术中未输血被当作对照,共余230例均完成了24周随访和各项检测。 230例中,女,135例,平均年龄为43.6岁(10-66岁);男,95例,平均年龄为41.5岁(9-66岁)。所有病人分别在每次输血前、手术后两个月内每2周、和以后每月抽血一次进行检测。230例患者共输血936单位,平均每人输血4.06单位(1-30单位)。所输血液均采自用被动血凝法检测乙型肝炎表面抗原(HBsAg)阴性的自愿献血员。
Hepatitis is the most common complication of transfusion therapy. In a prospective cohort of 307 patients who underwent cardiopulmonary bypass during cardiac surgery in Spain from October 1978 to August 1981, the incidence of hepatitis after blood transfusion was investigated. 62 cases were eliminated due to various reasons, 15 cases were not transfused as a control during surgery, a total of 230 cases were completed 24 weeks follow-up and various tests. Of the 230 patients, 135 were female, with an average age of 43.6 years (range, 10-66 years); 95 were male, with an average age of 41.5 years (range, 9-66 years). All patients were tested before each blood transfusion, two months after surgery, every two weeks, and once a month for blood tests. A total of 230 patients received 936 units of blood transfusion, with an average of 4.06 units (1-30 units). All blood transfusions were collected from voluntary blood donors who tested positive for hepatitis B surface antigen (HBsAg) by passive clotting.