铬是人体必需元素之一,但是六价铬对人体有毒性作用。少不报道认为六价铬干扰许多重要酶的活性,损伤肝和肾脏,可诱发肺癌等恶性肿瘤。但六价铬化合物对心、脑及内分泌腺等组织脏器病理形态学方面的研究报道很少,尤其是不同剂量铬对全身各脏器的感受性及各脏器内铬蓄积量与病变的关系尚不清楚。根据图们江水系污染情况,我们进行了亚急性及慢性六价铬毒性实验。本文着重研究全身主要脏器的病变性 Chromium is one of the essential elements of the human body, but hexavalent chromium is toxic to the human body. It is not reported that hexavalent chromium interferes with the activities of many important enzymes, damages the liver and kidneys, and can induce malignant tumors such as lung cancer. However, there have been few reports on the pathomorphology of organs such as heart, brain, and endocrine glands by hexavalent chromium compounds, especially the sensitivity of different doses of chromium to body organs and the relationship between chromium accumulation in various organs and lesions. still not clear. According to the Tumen River water pollution, we conducted subacute and chronic hexavalent chromium toxicity experiments. This article focuses on the pathological changes of the main organs of the whole body