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原发性肝癌(以下称肝癌)切除最常用的控制入肝血流的方法是Pringle法(即同时阻断肝动脉和门静脉)。但由此而导致的肝细胞继发缺氧性损伤使术后恢复很不平稳,甚至可能导致肝功能衰竭而死亡。1992年2月以来,作者应用选择性入肝血流阻断法(即只阻断门静脉,不阻断肝动脉)控制入肝血流切除合并肝硬化的肝癌122例(A组),随机抽取既往应用Pringle法切除合并肝硬化的肝癌122例为对照组(B组),就术中出血量、术后主要血液生化指标的改变、术后并发症和手术死亡率等进行了对比性研究和讨论,报告如下。 1 资料 122例中男109例,女13例,男女之比为8.4:1。年龄12～68岁,平均47.7岁。肝细胞癌111例,胆管
Resection of primary liver cancer (hereinafter referred to as hepatic cancer) The most commonly used method for controlling blood flow to the liver is the Pringle method (that is, the simultaneous blocking of the hepatic artery and the portal vein). However, the resulting hypoxic injury secondary to hepatocytes leads to a very unstable recovery and may even lead to liver failure and death. Since February 1992, the authors applied selective hepatic artery occlusion (that is, only the portal vein was blocked, and the hepatic artery was not blocked). 122 patients (group A) with hepatocellular carcinoma who underwent hepatic resection and hepatic cirrhosis were randomly selected. In the past, 122 patients with liver cirrhosis were treated with Pringle method as a control group (B group). A comparative study was conducted on the intraoperative blood loss, postoperative blood biochemical changes, postoperative complications, and operative mortality. Discussions are as follows. 1 data 122 cases of 109 males and 13 females, male to female ratio of 8.4:1. Age 12 to 68 years old, average 47.7 years old. 111 cases of hepatocellular carcinoma, bile duct