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目的:分析甲型H1N1流感病毒裂解疫苗(下称“甲流疫苗”)接种后药物不良反应(ADR)的发生情况。方法:采用Excel 2003版软件,将2009年9月15—25日接种“甲流疫苗”的1173例各类人员的一般情况,ADR发生时间、持续时间,发生率与转归等进行统计分析。结果:1173例“甲流疫苗”接种者中62例出现ADR,发生率为5.28%,其中局部反应发生率为3.67%,全身反应发生率为1.62%。所有报告病例均为非严重性,全部病例均在短时间内恢复正常,无严重接种不良反应发生。结论:“甲流疫苗”的不良反应发生率低,且反应轻微,安全性较高,可用于人群的大规模预防接种及疫情应急接种。
Objective: To analyze the incidence of Adverse Drug Reaction (ADR) after inoculation of Influenza A H1N1 influenza virus (“A” vaccine). Methods: The Excel 2003 version of the software, the September 15-25, 2009 inoculation “A flu vaccine” of the 1173 cases of various types of general staff, ADR time, duration, incidence and outcome statistics analysis. Results: ADR occurred in 62 out of 1173 cases of “Influenza A vaccine” vaccines, with a rate of 5.28%. The incidence of local reactions was 3.67% and the incidence of systemic reactions was 1.62%. All reported cases were non-serious, all cases returned to normal in a short time, no serious adverse reactions to vaccination occurred. Conclusion: The incidence of adverse reactions of “A flu vaccine” is low, and the reaction is mild with high safety. It can be used in large-scale vaccination and emergency vaccination.