梅毒性阵发性冷性血红蛋白尿为罕见之疾病,自 Dressler 氏首先于1854年描述此病以来,在国外已报告350余例。在国内文献中首先由 S.Inamor 及N.Ito 二氏报告2例,嗣后陆续有零星病例报告,迄1958年底总共报告11例,其中儿童占7例。有关本病的疗法目前尚无统一意见。我院儿科于1957年冬季曾应用大剂量青霉素治癒1例,特报告供参考。 Syphilitic paroxysmal cold hemoglobinuria is a rare disease that has been reported abroad since Dressler’s first description of the disease in 1854. In the domestic literatures, 2 cases were first reported by S. Inamor and N.Ito II, followed by sporadic case reports. By the end of 1958, a total of 11 cases were reported, of which 7 cases were children. The current treatment of the disease there is no uniform opinion. Pediatrics in our hospital in 1957 winter had a large dose of penicillin cure 1 case, special report for reference.