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目的正确识别多原发癌(MPC)。方法经计算机病案检索系统从1796例消化道、肺和乳腺等癌症患者中查找MPC病例。结果共查出72例MPC病例,三病种的总发生率为4.0%(72/1796)。其中消化道癌症患者中MPC的发生率为5.5%(45/820);肺癌为3.3%(18/540);乳腺癌为2.1%(9/436)。结论MPC与转移癌或复发癌在治疗上有原则性区别,因为前者仍有机会争取根治性治疗,而后者一般仅为姑息性治疗,两者预后有所不同。
Objective To correctly identify multiple primary cancers (MPC). Methods A computerized medical record retrieval system was used to find MPC cases from 1796 cases of cancer patients such as digestive tract, lung and breast. Results A total of 72 cases of MPC were detected. The overall incidence of the three diseases was 4.0% (72/1796). The prevalence of MPC in patients with gastrointestinal cancer was 5.5% (45/820); lung cancer was 3.3% (18/540); breast cancer was 2.1% (9/436). Conclusions There is a principled difference in the treatment of MPC with metastatic or recurrent cancer because the former still has the opportunity to fight for radical treatment, while the latter is generally only palliative and the prognosis is different.