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目的探讨美托洛尔治疗慢性心力衰竭的临床疗效。方法选取宜春市奉新第二中医院2014年1月—2015年1月收治的慢性心力衰竭患者116例,随机分为干预组和对照组,各58例。对照组给予常规治疗,干预组在常规治疗的基础上联合美托洛尔治疗,观察两组使用3个月后心功能改善情况、左室舒张末内径(LVDD)、左室射血分数(LVEF)、血压变化及心率情况。结果干预组总有效率为96.6%,高于对照组的82.8%,差异有统计学意义(P<0.05)。治疗前两组血压、心率比较,差异无统计学意义(P>0.05);治疗后干预组血压、心率低于对照组,差异有统计学意义(P<0.05)。治疗前两组LVDD和LVEF比较,差异无统计学意义(P>0.05);治疗后干预组LVDD低于对照组,LVEF高于对照组,差异有统计学意义(P<0.05)。结论美托洛尔治疗慢性心力衰竭可以有效改善患者心功能,调节心率,临床效果好。
Objective To investigate the clinical efficacy of metoprolol in the treatment of chronic heart failure. Methods A total of 116 patients with chronic heart failure who were admitted to Fengxin Second Hospital of Traditional Chinese Medicine from January 2014 to January 2015 in Yichun City were randomly divided into intervention group and control group, 58 cases each. The control group was given routine treatment. The intervention group was treated with metoprolol on the basis of routine treatment. The improvement of cardiac function, left ventricular end-diastolic diameter (LVDD), left ventricular ejection fraction (LVEF) ), Changes in blood pressure and heart rate. Results The total effective rate in the intervention group was 96.6%, which was higher than that in the control group (82.8%), the difference was statistically significant (P <0.05). There was no significant difference in blood pressure and heart rate between the two groups before treatment (P> 0.05). The blood pressure and heart rate of intervention group were lower than those of control group after treatment (P <0.05). There was no significant difference in LVDD and LVEF between the two groups before treatment (P> 0.05). LVDD in intervention group was lower than that in control group after treatment, and LVEF was higher than that in control group (P <0.05). Conclusion Metoprolol treatment of chronic heart failure can effectively improve cardiac function, heart rate, clinical effect is good.