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目的比较分析阿托伐他汀与辛伐他汀治疗2型糖尿病合并冠心病患者的临床效果。方法研究对象选取80例老年2型糖尿病合并冠心病患者,随机将其平均分为两组。两组均进行常规治疗,在此基础上对照组应用辛伐他汀治疗,观察组采用阿托伐他汀进行治疗,并对比其临床治疗效果。结果观察组患者的总有效率为97.50%,远高于对照组患者的70.00%,差异有统计学意义(P<0.05)。观察组患者治疗后的射血分数为(48.21±8.50)%,明显高于治疗前,差异具有统计学意义(P<0.05)。而对照组射血分数治疗前后相比无明显变化,差异未见统计学意义(P>0.05)。结论与辛伐他汀相比,阿托伐他汀在治疗老年2型糖尿病合并冠心病方面有较好的临床治疗效果,有助于提高患者的射血分数,安全可靠,可在临床上推广使用。
Objective To compare the clinical effects of atorvastatin and simvastatin in patients with type 2 diabetes mellitus complicated with coronary heart disease. Methods Subjects Eighty elderly patients with type 2 diabetes mellitus complicated with coronary heart disease were selected and randomly divided into two groups. Both groups were treated routinely, on this basis, the control group was treated with simvastatin, the observation group was treated with atorvastatin, and compared its clinical effect. Results The total effective rate of the observation group was 97.50%, which was much higher than that of the control group (70.00%), the difference was statistically significant (P <0.05). The ejection fraction after treatment in the observation group was (48.21 ± 8.50)%, which was significantly higher than that before treatment (P <0.05). There was no significant difference between before and after treatment in the control group (P> 0.05). Conclusion Compared with simvastatin, atorvastatin has better clinical efficacy in the treatment of type 2 diabetes mellitus with coronary heart disease in elderly patients. It is helpful to improve the ejection fraction, safety and reliability and can be widely used clinically.