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我们试图从免疫学角度讨论职业中毒的本质,而对铅作业者的细胞免疫功能进行了测定。当前,关于直接接触铅等重金属的现场工人的免疫功能还没有报告。因此,此次对直接接触铅的工人的免疫功能,特别是细胞免疫方面的功能进行了研究。方法是使用据说对细胞免疫的功能细胞——淋巴细胞具有非特异性分裂刺激作用的植物血凝素。进行微量全血培养然后测定T细胞的逆转功能。即把所采取的血液不加任何处理就用培养液稀释10倍。加入植物血凝素(PHA)诱发逆转反应。取PHA的剂景。比较研究彼此之间最高反应率结果,确认铅作业工人与正常人比较,转化反应具有有意义的低下。尤其,在铅浓度高的作业现场尿中合铅量高的
We tried to discuss the nature of occupational poisoning from the perspective of immunology and determined the cellular immunity of lead workers. At present, there is no report on the immune function of field workers who are in direct contact with heavy metals such as lead. Therefore, this study explored the immune function of workers exposed to lead directly, particularly their cellular immunity. The method is to use phytohemagglutinin, which is said to have a nonspecific disruptive stimulus to cellular lymphocytes, which are said to be functional cells. Micro-whole blood culture was performed and the T cell reverse function was measured. That is to take the blood without any treatment diluted 10 times with the culture medium. Phytohemagglutinin (PHA) is added to induce reversal reaction. PHA take the scene. A comparative study of the highest response rates among each other confirms that lead workers have a meaningful low conversion response compared with normal controls. In particular, the high lead concentration in the workplace of high levels of lead in lead