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瑞典医药品有害委员会报道了氯头孢菌素与其它头孢菌素类抗生素不同的过敏反应。其中皮肤反应占64%,包括荨麻疹、发疹、多形性红斑,另许还发现16例关节痛、关节肿胀,5例血清疾患型反应患者。在报道的109例不良反应中,50%是0～4岁的小孩,绝大多数是只用过氯头孢菌素一种药物。该委员会对因上呼吸道感染而应用氯头孢菌素或羟氨苄青霉素的2000名小孩(其中75%为0～3岁)的不良反应进行了调查。氯头孢菌素和羟氨苄青霉素的过敏反应发生率分别是5.3和3.7%,没有显著差异,但血清疾患样反应、多形性红斑和荨麻疹的发生率
The Swedish Pharmaceutical Hazard Committee reported a different allergic reaction of chlorceparin to other cephalosporin antibiotics. The skin reaction accounted for 64%, including urticaria, rash, erythema multiforme, and may also found 16 cases of joint pain, joint swelling, 5 patients with serum-type response. Of the 109 reported adverse events, 50% were children 0 to 4 years old, the vast majority of whom had been treated with a single-dose cephalosporin. The committee investigated the adverse effects of 2,000 children (75% of whom were 0-3 years old) who received cefaclor or amoxicillin for upper respiratory tract infections. The incidence of anaphylactic reactions with chlorcepham and amoxicillin was 5.3 and 3.7%, respectively, with no significant difference, but the incidence of seronegative reactions, erythema multiforme and urticaria