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作者特地观察了非肺源性病因(如脓毒病)或在12小时内发生弥漫性血管内凝血所致的ARDS患者。应用支气管肺泡灌洗法作为以肺泡腔中获取典型样品的方法。把ARDS患者的灌洗液与相同人数的或“正常的”不吸烟志愿者的灌洗液进行对照。材料和方法对10例确诊为ARDS的患者以及11例不吸烟志愿者施行支气管肺泡灌洗术。列为研究对象的ARDS患者须符合下列标准:1) 静态肺顺应性≤水的50ml/cm;2) 肺毛细血管楔压≤12mmHg;3) 灌洗液中未培养出病原体;4) 从插管到肺泡灌洗≤12小时。一旦纤支镜插入外周气道,即灌入总量300ml的生理盐水,用纤支镜获取灌洗物。首先对灌洗物作细胞计数,接着2次离心弃去细胞和脂质碎
The authors specifically looked at non-pulmonary causes (such as sepsis) or patients with ARDS due to disseminated intravascular coagulation within 12 hours. Bronchoalveolar lavage is used as a method to obtain typical samples in the alveolar space. The lavage of ARDS patients was compared to the lavage of the same number of or “normal” non-smoking volunteers. Materials and Methods Bronchoalveolar lavage was performed on 10 patients diagnosed with ARDS and 11 non-smoking volunteers. ARDS patients included in the study should meet the following criteria: 1) static lung compliance ≤ water 50ml / cm; 2) pulmonary capillary wedge pressure ≤ 12mmHg; 3) lavage fluid is not cultured in the pathogens; 4) Tube to alveolar lavage ≤ 12 hours. Once the fiberoptic bronchus inserted into the peripheral airway, that is infused with a total volume of 300ml of saline, with bronchoscopy to obtain lavage. The lavage was first counted for cells and then centrifuged twice to discard cells and lipid fragments