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应用重组α-干扰素(α-IFN)治疗慢性乙肝可诱生自身抗体。尽管这些抗体似乎为非慢性活动性肝炎相关抗体,然而,这些自身抗体的产生可能加重肝脏病变。为此,作者选择31例经α-IFN 治疗的慢性活动性肝炎患者进行研究。
Application of recombinant interferon alpha (IFN-α) in the treatment of chronic hepatitis B can induce autoantibodies. Although these antibodies appear to be non-chronic active hepatitis-related antibodies, the production of these autoantibodies may aggravate liver disease. To do this, the authors selected 31 patients with chronic active hepatitis treated with alpha-IFN.