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单链抗体 (scFv)是目前报道最多的一类小分子抗体 ,对科研及疾病的诊断和治疗有重要意义。本文介绍了scFv在大肠杆菌周质腔及培养基中分泌型表达的特点、影响因素及研究进展
Single-chain antibody (scFv) is the most widely reported class of small molecule antibodies, for scientific research and disease diagnosis and treatment of great significance. In this paper, the characteristics, influencing factors and research progress of scFv expression in the periplasm and medium of Escherichia coli