目的： 探讨氟桂嗪（ｆｌｕｎａｒｉｚｉｎｅ ，ＦＮＺ） 对内耳缺血的保护作用。方法： 采用结扎双侧椎动脉和一侧颈总动脉制备内耳缺血模型，用戴树宏耳蜗铺片术观察耳蜗形态学改变，将预防用药组与缺血组进行对比，结果： 缺血组平均每耳外毛细胞损失６３ 个，预防用药组每耳外毛细胞损失约９ 个，经ｔ 检验，差异显著（ Ｐ＜ ００１） 。结论：ＦＮＺ 对内耳缺血时外毛细胞损伤具有保护作用 Objective: To investigate the protective effect of flunarizine (FNZ) on the ischemia of the inner ear. Methods: The ligation of bilateral vertebral artery and the common carotid artery on one side of the preparation of the inner ear ischemia model, with cochlear cochlear implant surgery morphological changes were observed, the prophylaxis group and the ischemic group were compared, the results: There were 63 out-of-ear hair loss cells and about 9 out-of-ear hair loss cells in prophylaxis group. The t-test showed significant difference (P <001). Conclusion: FNZ has a protective effect on the injury of outer hair cells in the inner ear ischemia