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血卟啉衍生物(Hematophorphyrin-derivati-ve;HPD)处理-激光照射导至活体细胞死亡,这种作用在肿瘤细胞比其周围正常组织更为明显,为阐明这一现象的细胞学基础,有必要用来源一致的离体培养正常和恶性转化细胞进行比较.实验用大鼠甲状腺建立的离体快速生长、分化(摄取碘及合成甲状腺素)的正常细胞系FRTL-5及由它经RNA 肿瘤病毒Ki-MSV(Ki-MuLV)感染使之恶性转化的细胞系
Hematoporphyrin-derivati-ve (HPD) treatment-laser irradiation leads to the death of living cells. This effect is more pronounced in tumor cells than in surrounding normal tissues. To clarify the cytological basis of this phenomenon, there are It is necessary to compare the normal and malignant transformed cells cultured in vitro with the same source. Experimental The normal cell line FRTL-5 established by the rat thyroid gland to rapidly grow, differentiate (uptake of iodine and synthetic thyroxine) and RNA interference from it Virus Ki-MSV (Ki-MuLV) Infected Cell Lines That Caused Malignant Transformation