论文部分内容阅读
目的 :研究脑出血后脑水肿形成的特点。方法 :建立大鼠尾状核出血模型 ,用干湿重法分别测定不同部位的脑组织在出血后1 ,2 ,3 ,5 ,7d的脑组织水分含量的变化 ,并与正常脑组织对比。结果 :脑出血后 2 4h内在血肿同侧基底节区及血肿同侧对应的皮质区形成明显的水肿 ,水肿的高峰在第 3天 ,持续 1周仍不消退 ,而血肿对侧对应的基底节区及皮质区脑组织水分含量则无明显变化。结论 :大鼠脑出血后脑水肿在 2 4h内形成 ,第 3天达到高峰 ,提示对临床脑出血病人脑水肿的防治要尽可能早
Objective: To study the characteristics of cerebral edema after intracerebral hemorrhage. Methods: The model of caudate nucleus haemorrhage in rats was established. The changes of water content of brain tissue in different parts of the brain at 1, 2, 3, 5 and 7 days after hemorrhage were respectively determined by dry-wet method and compared with normal brain tissue. Results: Within 24 hours after intracerebral hemorrhage, there was obvious edema in the ipsilateral basal ganglia and ipsilateral corresponding cortical area of hematoma. On the third day, the peak of edema persisted for one week, while the contralateral basal ganglia Regional and cortical brain water content did not change significantly. Conclusion: Cerebral edema occurred within 24 hours after intracerebral hemorrhage in rats and peaked on the third day, suggesting that prevention and treatment of cerebral edema in patients with clinical cerebral hemorrhage should be as early as possible