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已知在手术控制出血前,输液复苏可以加速出血,因为血压升高和凝血因子稀释的缘故。为了观察输入等渗盐水对血液凝固的影响,作者进行以下的实验研究,取24只SD雌鼠,分成4组:（1）A组,不复苏;(2)B、C和D组均为复苏组,分别输入等渗盐水40ml/kg·4min、80ml/kg·4min和80ml/kg·lmin。自颈动脉和颈静脉内置管以供采血样、血流动力学测定和输液之用。切除鼠尾75％,制成出血模型,并收集出血血液以测定其丧失量,作各项凝血因子测定,包括凝血酶原时间（PT）、活化部分促凝血酶原激酶时间（APTT）、纤维蛋白原和血小板计数。
It is known that transfusion resuscitation can accelerate bleeding prior to surgical control of bleeding because of elevated blood pressure and dilution of clotting factors. In order to observe the effects of isotonic saline infusion on blood coagulation, the authors conducted the following experimental studies: 24 female SD rats were divided into 4 groups: (1) group A, without resuscitation; (2) groups B, C and D were In the recovery group, isotonic saline (40ml / kg · 4min, 80ml / kg · 4min, and 80ml / kg · lmin, respectively) Tubes were placed in the carotid and jugular vein for blood sampling, hemodynamic determination, and infusion. 75% of the tail was excised, a bleeding model was made and hemorrhagic blood was collected to measure the loss, and various clotting factors were measured including prothrombin time (PT), activated partial thromboplastin time (APTT), fiber Progeny and platelet count.