口服硝苯啶和可乐定常用于高血压急诊的治疗,然而对同样对象的对比研究至今缺如。作者复习急诊室于1987年10月1日至1988年12月30日间高血压患者的治疗记录。入选标准为舒张压(DBP)>15.3kPa且无终未器官的急性损害。患者分为三组。N组35例口服硝苯啶10mg,必要时每小时再服10mg。C组32例口服可乐定0.1或 0.2mg,必要时每小时再服0.1或0.2mg。G_3组口服1种其他药物,或者口服1～2种其他药物加硝苯啶或可乐定。安全有效的标准是DBP<14.6kPa而平均动脉压(MBP)下降< Oral nifedipine and clonidine are often used in the treatment of hypertensive emergency, however, the comparative study of the same subject has so far lacked. The authors reviewed the emergency room treatment records from October 1, 1987 to December 30, 1988 for hypertensive patients. Inclusion criteria were diastolic blood pressure (DBP)> 15.3 kPa and no end-organ dysfunction. Patients were divided into three groups. N group 35 patients oral nifedipine 10mg, if necessary, and then take 10mg per hour. C group of 32 oral clonidine 0.1 or 0.2mg, if necessary, 0.1 or 0.2mg per hour and then. G_3 group oral administration of 1 other drugs, or oral administration of 1 to 2 other drugs plus nifedipine or clonidine. Safe and effective criteria are DBP <14.6 kPa and mean arterial pressure (MBP) <