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近年,我们在上海第一医学院附属华山医院医疗小分队指导下,配制了15%尿素乳膏,治疗手足皲裂。经我院三年多临床应用,获得较为满意的效果,很受患者的欢迎。现简介其配制方法。处方~*尿素 150g单硬脂酸甘油酯 100g白凡士林 50g地蜡 100g液状石蜡 500g司盘-40(或司盘-60) 2.5g乳化剂 OP 5g尼泊金乙酯 1g2,6-叔丁基对甲酚(BHT) 0.15～0.25g蒸溜水 250ml制法:(1)油相的制备:将单硬脂酸甘油酯、地蜡、自凡士林加热,俟全部熔化后加入液状石蜡,一层纱布过滤,再加入尼泊金乙酯、司盘-40、BHT,充分搅匀,使保持75～80℃之间。
In recent years, we under the guidance of the Huashan Hospital Medical Unit affiliated to Shanghai First Medical College, formulated a 15% urea cream to treat chapped hands and feet. After more than three years of clinical application in our hospital, access to more satisfactory results, very popular with patients. Now describes the preparation method. Prescription ~ * Urea 150g Glyceryl monostearate 100g White petrolatum 50g Ceresin 100g Liquid paraffin 500g Span-40 (or Span-60) 2.5g Emulsifier OP 5g Ethyl paraben 1g 2,6-tert-Butyl Cresol (BHT) 0.15 ~ 0.25g distilled water 250ml Preparation: (1) Preparation of the oil phase: glyceryl monostearate, wax, heated from vaseline, 俟 all melted by adding liquid paraffin, a layer of gauze Filtration, then add ethylparaben, Span-40, BHT, stir well, to maintain between 75 ~ 80 ℃.