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采用MTT法测定巨噬细胞的存活率，研究了小鼠腹腔注射云芝多糖（PSK）对腹腔巨噬细胞所受叔了基脂红过氧化物（tbOOH）损伤的保护作用的特点。结果显示，小鼠腹腔注射PSK对tbOOH造成的巨噬细胞损伤具有明显的保护作用。保护作用的效果与注射的次数无关，而与注射后取细胞的时间及注射的剂量有关，并在一定时间和剂量范围内呈现饱和性。体外将PSK与巨噬细胞共同温育，未发现其对巨噬细胞有保护作用。
The survival rate of macrophages was determined by MTT assay and the protective effect of PSK on peritoneal macrophages infiltration by tert-butyl lipid peroxide (tbOOH) was studied. The results showed that intraperitoneal injection of PSK in mice has a significant protective effect on tbOOH-induced macrophage injury. The effect of protection has nothing to do with the number of injections, but with the time after injection and the dose of injection, and in a certain time and dose range saturation. In vitro co-incubation of PSK with macrophages did not find its protective effect on macrophages.