为重新评价阿苯达唑对泡球蚴的杀虫作用，将３４只沙鼠腹腔内移植感染泡球蚴后，随机分成３个治疗组和３个对照组，分别于感染后３０ｄ、５０ｄ和７ｄ用含阿苯达唑００５％的药饵喂饲（剂量５０ｍｇ／ｋｇ／ｄ），连续治疗６、１０和７月，停药３月后解剖。结果显示３个治疗组的泡球蚴组织较对照组明显缩小，重量下降，减重率分别为８６７％、９３３％和９５７％，其中有３／６、３／６和４／５的沙鼠中泡球蚴重量明显低于感染时的０１ｇ。同时发现有１３只治疗组沙鼠泡球蚴涂片镜检无活的原头节。病理学检查显示泡球蚴组织结构受到严重破坏，囊泡塌陷，生发膜坏死脱落，原头节崩解与钙化，形成异物肉芽肿和纤维化。实验表明，阿苯达唑不仅抑制泡球蚴的生长，而且也具有杀死泡球蚴的作用 In order to re-evaluate the insecticidal effect of albendazole on Echinococcus granulosus, 34 gerbils were transplanted intraperitoneally for infection of metacercariae and then randomly divided into three treatment groups and three control groups, respectively. After 30d, 50d and 7d with albendazole 0  05% of the bait fed (dose 50mg / kg / d), continuous treatment of 6,10 and 7 months, stopping 3 months after the anatomy. The results showed that the Echinococcus granulosus tissue of the three treatment groups was significantly reduced compared with the control group, weight loss, weight loss rates were 86.7%, 93.3% and 95.7%, respectively, of which 3 / 6,3 / 6 and 4/5 of the gerbil in Echinococcus weight was significantly lower than infection 0  1g. At the same time, there were 13 treatment groups of gerbil hydatid lavage smear microscopy of the original head. Pathological examination showed that the tissue structure of Echinococcus granulosus was severely damaged, vesicles collapsed, germinal membrane necrosis, disintegration and calcification of the original head section, the formation of foreign body granuloma and fibrosis. Experiments show that albendazole not only inhibit the growth of metacercariae, but also have the role of killing metacercariae