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作者比较了接受静脉内链激酶治疗(SK)与接受常规治疗的急性心肌梗塞(AMI)患者出院前的左室功能,分析再灌注状态及非梗塞区血管的解剖,着重于溶栓治疗对局部室壁功能的影响。方法:368例 AMI患者随机分为接受静脉内SK 150万U(SK组)及常规治疗(常规组)。全部符合以下条件:年龄<75岁,症状出现<6小时,心电图STv_(1-3)抬高>1.5mv,或其它导联>1mv。从症状出现到开始治疗的平均时间为209分,42.9％<3小时。SK组138例(72.3％)和常规组112例(63.3％)于A·MI后10.4±7.4天行冠脉及左室造影,170例的造影可供分析,其中49例为前壁,121例为下壁。对每例进行了总体和局部左室收缩功能定量分析。运用微型计算机对30度右前斜位左室造影描记舒张期末和收缩期末左室心内膜周边,计算总体喷血分数(E-F)。采用中线法计算各节段的运动。同时建立一52例正常人节段活动范围数字模式图,以供本实验对
The authors compared pre-discharge left ventricular function in patients receiving intravenous streptokinase (SK) and routinely treated acute myocardial infarction (AMI), analyzed reperfusion status and anatomy of non-infarcted blood vessels, and focused on the effect of thrombolysis on local Wall function of the impact. Methods: Thirty-six patients with AMI were randomly assigned to receive SK 1.5 million U (SK group) and conventional therapy (conventional group). All of the following conditions were fulfilled: age <75 years, symptom onset <6 hours, electrocardiogram STv_ (1-3) elevation> 1.5 mv, or other leads> 1 mv. The average time from symptom onset to initiation of treatment was 209 and 42.9% <3 hours. One hundred and thirty-eight patients (72.3%) in the SK group and 112 patients (63.3%) in the conventional group underwent coronary artery and left ventricular imaging at 10.4 ± 7.4 days after AMI. Angiography of 170 patients was available for analysis, of which 49 were anterior wall and 121 Example for the next wall. Quantitative analysis of global and regional left ventricular systolic function was performed for each case. The total ejection fraction (E-F) was calculated using a microcomputer on the left ventricular end-diastole at the 30-degree right anterior oblique oblique ventricular end-diastole and at the end of systole. The midline method is used to calculate the motion of each segment. At the same time, we established a digital pattern diagram of the activity range of 52 normal persons for this experiment