论文部分内容阅读
肿瘤部位出现大量淋巴细胞浸润的病人常有较好的预后 ,推测这是宿主对肿瘤相关抗原的一种直接反应。目前理想的检测是否存在针对肿瘤细胞的克隆性增殖T细胞的方法是CDR3长度分析法。克隆性增殖T细胞的研究有助于进一步阐明肿瘤免疫机制 ,并有可能用于过继细胞免疫治疗
Patients with a large number of lymphocytic infiltrate at the tumor site often have a good prognosis, presumably this is a direct response of the host to tumor-associated antigens. The current ideal method for detecting the presence of clonally proliferating T cells against tumor cells is the CDR3 length assay. The study of cloned proliferating T cells is helpful to further elucidate the mechanism of tumor immunity and may be used for adoptive cellular immunotherapy.