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目的探讨二甲双胍联合甘精胰岛素在2型糖尿病患者中血糖和血脂控制的疗效。方法对新疆自治区职业病医院门诊和住院60例2型糖尿病患者原使用磺脲类或格列奈类药物治疗血糖控制不良患者改用二甲双胍联合甘精胰岛素前后自身对照血糖,血脂控制疗效评价。结果2型糖尿病患者使用二甲双胍联合甘精胰岛素血糖,血脂控制优于使用磺脲类或格列奈类,差异有统计学意义(P<0.05)。结论2型糖尿病患者二甲双胍联合长效胰岛素治疗效果好。
Objective To investigate the effect of metformin combined with insulin glargine on type 2 diabetes patients with blood glucose and lipid control. Methods Sixty patients with type 2 diabetes in outpatient and inpatient hospital of occupational disease hospital of Xinjiang Uygur Autonomous Region were treated with sulfonylureas or glinides in the treatment of patients with poor glycemic control before and after their use of metformin combined with insulin glargine before and after their own control blood glucose and lipid control efficacy evaluation. Results Patients with type 2 diabetes mellitus were treated with metformin combined with insulin glargine. The blood lipid control was better than that of sulfonylureas or glinides, with statistical significance (P <0.05). Conclusion Type 2 diabetes mellitus combined with long-acting insulin is effective.