论文部分内容阅读
目的 探索围术期输血对胃癌根治术患者预后及免疫的影响.方法 选择2014G5-2015G5期间收治的100例胃癌根治术患者为此次研究对象,根据输血与否分为观察组(围术期输血患者;50例)和对照组(围术期未输血患者;50例),对所有患者术后进行化疗药物辅助治疗.结果 经一年随访发现,观察组和对照组之间对比死亡率、复发率、术后CD4/CD8比值(P<005),同时输血可作为患者生存期的一个强有力的预测因素.结论 围术期输血对胃癌根治术患者预后具有一定影响,可降低患者免疫功能,对于必须进行输血治疗患者,应严格控制输血指征.
Objective To explore the effect of perioperative blood transfusion on the prognosis and immunity of gastric cancer patients undergoing radical operation.Methods 100 cases of radical resection of gastric cancer admitted during 2014G5-2015G5 were selected as the study subjects and divided into observation group (perioperative blood transfusion 50 patients) and control group (50 patients without perioperative blood transfusion) .All the patients were treated with adjuvant chemotherapeutic drugs after operation.Results After one year follow-up, it was found that the comparative mortality and relapse between the observation group and the control group (P <0.05), and the postoperative CD4 / CD8 ratio (P <005), meanwhile blood transfusion could be a powerful predictor of survival.Conclusion Perioperative blood transfusion has some effects on the prognosis of gastric cancer patients with radical surgery, which can reduce the immune function, For patients who must be transfused, strict indication of blood transfusion should be administered.