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目的：建立风湿塞隆胶囊定性定量的分析方法。方法采用薄层色谱法(TLC)对诃子、丁香、白檀香进行定性鉴别；采用高效液相色谱法(HPLC)对红花中羟基红花黄色素A、木香马兜铃中马兜铃酸A进行含量测定。结果薄层色谱法均能检出诃子、丁香、白檀香；羟基红花黄色素A在浓度为9.47ug/ml~94.74ug/ml,羟基红花黄色素A的峰面积(A)与浓度(C)线性关系良好,相关系数r为0.9998；羟基红花黄色素A的回收率为97.96%(n=6),RSD为0.720%。马兜铃酸A的重现性好,其浓度在93.871ng/ml~938.71ng/ml,峰面积(A)与对照品浓度(C)线性关系良好。结论此方法专属性强,重现性好,可作为风湿塞隆胶囊定性定量的分析方法。“,”Objective To establish a rheumatism theron capsule qualitative quantitative analysis method. Methods Using thin layer chromatography (TLC) for qualitative identification myrobalan, clove, sandalwood incense; By high performance liquid chromatography (HPLC) on hydroxyl groups in saf lower saf lower yel ow pigment, A combination of aristolochic acid A in aristolochia content determination. Results TLC method can detect myrobalan, clove, sandalwood incense; A hydroxy saf lower yel ow pigment in the concentration of 9.47 ug/ml - 94.74 ug/ml range, hydroxy saf lower yel ow pigment of A peak area and concentration (C) (A) good linear relationship, cor elation coef icient r of 0.9998;Hydroxy saf lower yel ow pigment A recovery rate of 97.96% (n =6), RSD was 0.720%. Aristolochic acid A, good reproducibility, its concentration in the 93.871 ng/ml and 938.71 ng/ml range, peak area and reference substance concentration (C) (A) good linear relationship. Conclusion This method is specific, reproducible and can be used as rheumatism theron capsule qualitative quantitative analysis method.