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目的通过对2014~2016年北京市延庆区手足口病的病原学监测,了解北京市延庆区手足口病的流行特征,以便制定有效的防控措施。方法应用实时荧光定量PCR方法,对2014~2016年北京市延庆区门诊采集手足口病例咽拭子标本进行肠道病毒核酸检测,同时应用SPSS 19.0软件对检测结果进行统计学分析。结果 2014~2016年延庆区手足口病例肠道病毒核酸阳性率为78.69%(192/244);CoxA16、CoxA6、EV71、其他未分型肠道病毒病毒核酸阳性数分别为79份(32.37%)、17份(6.97%)、67份(27.46%)、29份(11.88%);2014~2016年手足口病高峰期均出现在6~7月;不同性别、年龄的病毒检测阳性率差异均无统计学意义(P>0.05)。结论 2014~2016年北京市延庆区手足口病的病毒核酸阳性率较高。
Objective To understand the epidemiological characteristics of HFMD in Yanqing District of Beijing from 2014 to 2016 and to monitor the etiology of HFMD in Yanqing District in Beijing in order to make effective prevention and control measures. Methods The real-time PCR method was used to detect throat swab samples of hand, foot and mouth from 2014-2016 outpatient clinics in Yanqing District of Beijing. The results of SPSS 19.0 software were used for statistical analysis. Results The positive rate of enterovirus nucleic acid in HFMD in Yanqing District was 78.69% (192/244) between 2014 and 2016; 79 (32.37%) were positive for CoxA16, CoxA6, EV71 and other non-parti- , 17 (6.97%), 67 (27.46%) and 29 (11.88%) respectively. The peak period of hand-foot-mouth disease occurred in June to July from 2014 to 2016. The positive rates of virus in different sexes and ages No statistical significance (P> 0.05). Conclusion The positive rate of virus nucleic acid in hand, foot and mouth disease in Yanqing District of Beijing from 2014 to 2016 was higher.