由发酵获得的6-氨基青霉素酸与各种合成的侧链相连后曾获得一系列新的半合成的青霉素。其中2,6-二甲氧苯基青霉素钠盐,代号X-1497,商品称Staphcillin,据初步研究发现具有显著抗青霉素酶的特性。本文系进一步从实验及临床加以研究。青霉素X-1497能对抗产生青霉素酶的葡萄球菌,所有被试验的50个菌株均在每毫升5 A series of new semisynthetic penicillins were obtained after the 6-aminopenicillanic acid obtained by fermentation was connected with various synthetic side chains. Among them 2,6-dimethoxyphenyl penicillin sodium salt, code X-1497, known as Staphcillin, according to preliminary studies have found that there is significant resistance to penicillinase. This article is further from the experimental and clinical research. Penicillin X-1497 against penicillinase-producing Staphylococcus aureus, all 50 strains tested were in 5 per ml