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近年来的研究表明,食用含有1,3-甘油二酯(1,3-DAG)的油脂可以降低脂肪积累、防止体重增加。但是天然存在的1,3-DAG很少,所以1,3-DAG的制备尤显重要。相对于化学法,生物酶法合成1,3-DAG具有反应条件温和、环境友好、产品质量好等优点,故近年来利用酶法合成1,3-DAG越来越受到关注。本文从用于制备的脂肪酶、制造方法和酶反应器等方面综述了国内外生物酶法制备1,3-DAG的相关研究进展,并指出降低酶的生产成本、延长酶的使用寿命等措施有助于促进生物酶法工业化生产1,3-DAG。
Recent studies have shown that consumption of fat containing 1,3-diglyceride (1,3-DAG) can reduce fat accumulation and prevent weight gain. However, there are few naturally occurring 1,3-DAGs, so the preparation of 1,3-DAG is of particular importance. Compared with the chemical method, the enzymatic synthesis of 1,3-DAG has the advantages of mild reaction conditions, environmental friendliness and good product quality. Therefore, the use of enzymatic synthesis of 1,3-DAG has drawn more and more attention in recent years. This review summarizes the research progress of 1,3-DAG from bio-enzymatic processes both at home and abroad, including the lipase used in the preparation, the manufacturing method and the enzyme reactor. It also points out the measures to reduce the production cost and prolong the service life of the enzyme Help to promote the enzymatic industrial production of 1,3-DAG.