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目的:对盐酸戊乙奎醚与阿托品治疗急性有机磷农药中毒的临床效果进行观察研究。方法:随机选择2015年9月~2016年9月时间范围商丘市第一人民医院接收的40例急性有机磷农药中毒患者,依据所实施不同用药治疗方法划分成两个组别,对照组20例实施阿托品治疗,研究组20例实施盐酸戊乙奎醚治疗,就两个组别临床效果进行观察比较。结果:研究组总有效率95.0%,对照组总有效率65.0%,两组之间差异明显(P<0.05);研究组乙酰胆碱酯酶恢复时间(3.3±1.1)d,对照组乙酰胆碱酯酶恢复时间(4.6±1.2)min,两组之间差异明显(P<0.05)。结论:盐酸戊乙奎醚应用于治疗急性有机磷农药中毒临床效果可观,具备临床推广价值。
Objective: To observe the clinical effect of penehyclidine hydrochloride and atropine on acute organophosphorus pesticide poisoning. Methods: Forty cases of patients with acute organophosphorus pesticide poisoning who were randomly selected from September 2015 to September 2016 in Shangqiu First People’s Hospital were divided into two groups according to the different methods of treatment: 20 cases in control group The implementation of atropine treatment, the study group of 20 cases of penehyclidine hydrochloride treatment, the clinical efficacy of the two groups were observed and compared. Results: The total effective rate was 95.0% in the study group and 65.0% in the control group, with significant difference between the two groups (P <0.05). In the study group, the recovery time of acetylcholinesterase (3.3 ± 1.1) d and the recovery of acetylcholinesterase Time (4.6 ± 1.2) min, the difference between the two groups was significant (P <0.05). Conclusion: Penehyclidine hydrochloride is effective in treating acute organophosphorus pesticide poisoning and has clinical value of popularization.