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目的探讨血塞通注射液治疗老年缺血性脑卒中的疗效及其对神经功能和血液流变学的影响。方法选取2015年2月—2016年5月徐州市贾汪区耿集卫生院收治的老年缺血性脑卒中患者74例,随机分为研究组和对照组,各37例。对照组给予常规治疗,研究组在常规治疗的基础上给予血塞通注射液治疗。比较两组患者临床疗效,美国国立卫生研究院卒中量表(NIHSS)评分及血液流变学指标。结果研究组总有效率高于对照组,差异有统计学意义(P<0.05)。治疗前,两组患者血浆黏度、血细胞比容、全血黏度高切、全血黏度低切和纤维蛋白原水平比较,差异无统计学意义(P>0.05)。治疗后,研究组血浆黏度、血细胞比容、全血黏度高切、全血黏度低切和纤维蛋白原水平低于对照组,差异有统计学意义(P<0.05)。治疗前两组患者NIHSS评分比较,差异无统计学意义(P>0.05);治疗后研究组NIHSS评分低于对照组,差异有统计学意义(P<0.05)。结论血塞通注射液能有效改善缺血性脑卒中患者血液流变学指标,减少神经功能缺损,促进神经功能的修复,提高治疗效果。
Objective To investigate the effect of Xuesaitong injection on senile ischemic stroke and its effect on neurological function and hemorheology. Methods From February 2015 to May 2016, 74 elderly patients with ischemic stroke admitted to Gengji Hospital, Jiawang District, Xuzhou City were randomly divided into study group and control group, 37 cases in each group. The control group was given routine treatment. The study group was given Xuesaitong injection on the basis of routine treatment. The clinical efficacy, NIHSS score and hemorheology of the two groups were compared. Results The total effective rate of the study group was higher than that of the control group, the difference was statistically significant (P <0.05). Before treatment, there was no significant difference in plasma viscosity, hematocrit, whole blood viscosity, low whole blood viscosity and fibrinogen level between the two groups (P> 0.05). After treatment, the study group plasma viscosity, hematocrit, whole blood viscosity cut, low blood viscosity and fibrinogen lower than the control group, the difference was statistically significant (P <0.05). There was no significant difference in the NIHSS score between the two groups before treatment (P> 0.05). After treatment, the NIHSS score of the study group was lower than that of the control group (P <0.05). Conclusion Xuesaitong injection can effectively improve the hemorheological parameters of ischemic stroke patients, reduce the neurological deficits, promote the repair of nerve function and improve the therapeutic effect.