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目的 分析江阴市2015-2016年疑似预防接种异常反应(AEFI)的发生特征,评价疫苗接种安全性和AEFI监测系统运转情况.方法 采用描述流行病学方法对江阴市2015-2016年报告的AEFI监测数据进行分析.结果 2015-2016年江阴市共报告AEFI个案641例,报告发病率为69.21/10万剂,其中包括一般反应579例,异常反应58例和偶合症4例.男、女性别比为1.31∶1;≤1岁组报告293例(占45.71％).夏季报告病例数最多,占37.75％,冬季报告最少,占16.85％.报告发病率前3位的一类疫苗分别为麻风疫苗(83例,215.32/10万剂次)、无细胞白百破疫苗(257例,174.46/10万剂次)和儿童白破疫苗(42例,139.47/10万剂次).结论 江阴市AEFI监测系统运转良好,监测敏感性、完整性、及时性均达到国家监测要求,但仍需采取综合性措施减少AEFI的发生.“,”Objective To analyze the features of adverse events following immunization (AEFI) in Jiangyin City from 2015 to 2016,and to evaluate immunization safety and the running status of AEFI monitoring system.Methods The descriptive epidemiology was adopted to analyze the AEFI data in Jiangyin City from 2015 to 2016.Results From 2015 to 2016,a total of 641 AEFI cases were reported(579 common cases,58 rare cases and 4 coincidental events).The mean eported incidence rate was 69.21/100 000 doses.The ratio of males and females was 1.31∶1.Among the total cases,45.71％ occurred to infants less than one-year old.The incidence of AEFI peaked in summer(37.75％) and was the lowest in winter(16.85％).The top 3 vaccines of the first kind were MR (83 cases,215.32/100 000 doses),DTP (257cases,174.46/100 000 doses) and DT (42cases,139.47/100 000 doses).Conclusion The AEFI surveillance performed well in Jiangyin City,with the sensibility,integrity and timeliness all arriving at the goals established by the country.However,the comprehensive measures are needed to reduce the incidence of AEFI.