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目的 探讨洗涤式自体血回输在微创小切口心脏外科手术中的安全性和可行性.方法 以2015年9月—2016年10月进行微创小切口心脏直视手术的50例患者为研究对象,根据术中是否进行自体血回输,分为自体血回输组26例,对照组24例.记录患者的一般资料、血常规、术中出血量、自体血回收量、术中异体血输入量、凝血功能、术后24 h纵膈引流量、住院时间等临床指标.结果 自体血回输组与对照组患者术前和术后24 h的红细胞压积(Hct)、血红蛋白(Hb)、血小板计数(PLT)及凝血酶原时间(PT)比较差异有统计学意义(P0.05);自体血回输组术中异体红细胞、血浆输入量明显少于对照组(P0.05).结论 洗涤式自体血液回输可有效减少心脏外科手术患者异体血输注,是一种经济、安全、实用的血液保护技术.“,”Objective To investigate the efficacy and safety of autologous blood transfusion in minimally invasive cardiac surgery. Methods Total of 50 cases with heart operation under cardiopulmonary bypass in the First Affiliated Hospital of Soochow University from September 2015 to October 2016, according to whether taking abstergent autologous blood transfusion or not, they were divided into two groups: Cell saver group consisting of 26 patients using cell saver device, and the remaining 24 patients without using the device served as control group. Retrospective analysis was made on the data of the basic information of patients, the volume of autologous blood transfusion, homologous blood transfusion, clotting pathway function, mediastinal drainage afar operation, hospitalization days etc. Results Compared with that of preoperative, there were statistically significant differences in Hb, Hct, PLT and PT (P<0.01), but the change between the two group has no significant difference. The volume of homologous blood transfusion in cell saver group were less than control group (P<0.01). 50 cases with surgery and postoperative recovery were smooth, no hemolysis, fever, allergies and other blood transfusion reaction, and there was no significant difference in mediastinal drainage afar operation, hospitalization days and the hospitalization expenses between the two groups. Conclusion Abstergent autologous blood transfusion used in cardiac surgery could effectively decreased the volume of homologous blood. And it is an economical, safe and practical blood conservation technology.