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A new Schiff base compound, C13H9Br2N3O2·CH3OH, isonicotinic acid [1-(3,5- dibromo-2-hydroxyphenyl)methylidene]hydrazide methanol, has been synthesized and characterized by elemental analysis, IR spectra, and single-crystal X-ray diffraction. The compound comprises a Schiff base moiety isonicotinic acid [1-(3,5-dibromo-2-hydroxyphenyl) methylidene]hydrazide and a methanol molecule. The crystal belongs to the triclinic system, space group P1 with a = 8.464(1), b = 9.511(2), c = 10.901(2) , α = 92.940(2), β = 110.456(2), γ = 96.040(2)o, Z = 2, V = 814.0(2) 3, Dc = 1.759 g/cm3, Mr = 431.09, λ(MoKα) = 0.71073 , μ = 4.994 mm-1, F(000) = 424, R = 0.0440 and wR = 0.1061. A total of 3284 unique reflections were collected, of which 2197 with I > 2σ(I) were observed. The molecule adopts a trans configuration about the C=N double bond. The dihedral angle between the benzene and pyridine rings is 22.0(4)o. The crystal structure is stabilized by intermolecular O-H···N and C-H···O hydrogen bonds, forming layers parallel to the ac plane. The preliminary biological tests show that the compound has potential antibacterial activities.
A new Schiff base compound, C13H9Br2N3O2 · CH3OH, isonicotinic acid [1- (3,5-dibromo-2-hydroxyphenyl) methylidene] hydrazide methanol, has been synthesized and characterized by elemental analysis, IR spectra, and single-crystal X-ray The compound comprises a Schiff base moiety isonicotinic acid [1- (3,5-dibromo-2-hydroxyphenyl) methylidene] hydrazide and a methanol molecule. The crystal belongs to the triclinic system, space group P1 with a = 8.464 (1 ), b = 9.511 (2), c = 10.901 (2) , α = 92.940 (2), β = 110.456 (2), γ = 96.040 (2) o, Z = 2 and V = 814.0 3, Dc = 1.759 g / cm3, Mr = 431.09, λ (MoKα) = 0.71073 , μ = 4.994 mm-1, F (000) = 424, R = 0.0440 and wR = 0.1061. A total of 3284 unique reflections were The molecule adopts a trans configuration about the C = N double bond. The dihedral angle between the benzene and pyridine rings is 22.0 (4) o. The crystal structure is stabilized by intermolecular OH ··· N and CH · · O hydrogen bonds, forming layers parallel to the ac plane. The preliminary biological tests show that the compound has potential antibacterial activities.