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目的对中西医结合与标准四联治疗幽门螺杆菌相关胃炎的临床疗效进行对比分析。方法 68例进行幽门螺杆菌相关胃炎治疗的患者,按照随机分配的原则分为对照组和观察组,各34例。对照组行常规四联疗法对幽门螺杆菌相关胃炎进行治疗,观察组行中西医结合方式对幽门螺杆菌相关胃炎进行治疗,对两组临床治疗效果及不良反应发生率进行对比。结果经过治疗后,对照组痊愈6例(17.65%)、有效22例(64.71%)、无效6例(17.65%),总有效率为82.35%;观察组痊愈11例(32.35%)、有效22例(64.71%)、无效1例(2.94%),总有效率为97.06%,观察组的治疗总有效率明显高于对照组,差异具有统计学意义(P<0.05)。观察组的不良反应发生率为8.82%,明显低于对照组的29.41%,差异具有统计学意义(P<0.05)。结论对幽门螺杆菌相关胃炎进行治疗时,采取中西医结合方式的治疗效果优于常规四联疗法,且能将不良反应发生率有效降低,安全性高,值得在临床上进一步推广应用。
Objective To compare the clinical curative effect of Helicobacter pylori-associated gastritis with traditional Chinese and Western medicine and standard quadruple therapy. Methods Sixty-eight patients with Helicobacter pylori-associated gastritis were divided into control group and observation group according to the principle of random distribution, 34 cases in each group. The control group received conventional quadruple therapy for the treatment of Helicobacter pylori-associated gastritis. The observation group was treated with combination of TCM and Western medicine for Helicobacter pylori-associated gastritis, and the clinical effects and the incidence of adverse reactions were compared between the two groups. Results After treatment, the control group recovered in 6 cases (17.65%), effective in 22 cases (64.71%), ineffective in 6 cases (17.65%), the total effective rate was 82.35%; the observation group cured in 11 cases (32.35%), effective 22 (64.71%), 1 case (2.94%) was ineffective and the total effective rate was 97.06%. The total effective rate of the observation group was significantly higher than that of the control group (P <0.05). The incidence of adverse reactions in the observation group was 8.82%, which was significantly lower than that in the control group (29.41%), the difference was statistically significant (P <0.05). Conclusions When Helicobacter pylori-associated gastritis is treated, the combination of TCM and Western medicine is superior to conventional quadruple therapy, and the incidence of adverse reactions can be effectively reduced and the safety is high. Therefore, it is worth further clinical application.