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胃腺瘤不常见,现将一例胃巨大腺瘤恶变报告如下。患者女,44岁。因上腹反复隐痛6个月,加重伴黑便1天入院经内科处理便血未见好转而转外科手术治疗。术中见胃窦部有一肿物,遂行胃大切手术。大体标本检查见近幽门的小弯侧,有一巨大息肉样肿物突出于胃腔中。肿物长11.5 cm,最大直径3.8 cm,基底部较宽,形成约4.6 cm的广蒂附于粘膜面。肿物较苍白,表面呈菜花状外观,其未端有一约2 cm大的出血坏死区,余胃组织未见特殊。镜下见肿物主要由大小较一致,排列较规则分化成熟的腺体构成,胞浆丰富,淡染,有粘液分泌现象。间质由富含血管的纤维组织构成,另有部
Gastric adenomas are uncommon, and one case of malignant glandular adenomas is reported below. The patient is 44 years old. Due to repeated abdominal pain on the abdomen for 6 months, aggravated with melena was admitted to hospital for 1 day and medical treatment of blood in the stool did not improve and was switched to surgical treatment. During the operation, there was a tumor in the gastric antrum, and a major gastrectomy was performed. For gross specimen examination, see the small curved side of the pylorus. There is a huge polypoid mass that protrudes from the stomach cavity. The tumor was 11.5 cm in length with a maximum diameter of 3.8 cm and the base was wide, forming a broad pedicle approx. 4.6 cm attached to the mucosal surface. The tumor was pale, with a cauliflower-like appearance on the surface. There was a hemorrhage and necrosis zone about 2 cm in diameter at the end of the tumor. The rest of the stomach tissue had no special appearance. Microscopically, the tumors were mainly composed of uniform and large-sized glands that were arranged in a regular and uniform manner. The cytoplasm was abundant, lightly stained, and mucus secretion was observed. The interstitial tissue is composed of vascular tissue, and