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目的：研究复方泻心汤的抗炎、镇痛作用。方法：通过观察复方泻心汤对巴豆油所致小鼠耳廓肿胀的 影响、对小鼠腹腔毛细血管通透性的影响、对乙酸刺激小鼠致痛的影响、对 K~+皮下致痛的影响，以阐明复方泻心汤 的抗炎、镇痛作用。结果：复方泻心汤能明显对抗巴豆油所致的炎症反应；显著抑制由乙酸引起的小鼠腹腔急性炎 症时毛细血管通透性的增加；对抗乙酸所致小鼠的疼痛性反应；明显提高由 K~+所致的大鼠致痛的电流值。结论： 表明复方泻心汤具有一定的抗炎、镇痛作用，可用于临床治疗因 HP 感染相关的胃炎、消化性溃疡等消化系统疾病。
Objective: To study the anti-inflammatory and analgesic effects of compound Xiexin Decoction. METHODS: The effect of compound Xiexin Decoction on the swelling of mice’s ear caused by croton oil, the effect on the capillary permeability of mice’s abdominal cavity, the effect of pain on acetic acid-stimulated mice, and the pain caused by K~+ subcutaneous were observed. The effect of eliminating the anti-inflammatory and analgesic effects of Fufang Xiexin Decoction. RESULTS: Compound Xiexin Decoction could significantly antagonize the inflammatory reaction induced by croton oil; markedly inhibited the increase of capillary permeability induced by acetic acid in mice with acute inflammation of abdominal cavity; and counteracted the painful response of mice induced by acetic acid; significantly improved The current value of pain induced by K~+ in rats. Conclusion: It is shown that compound Xiexin Decoction has certain anti-inflammatory and analgesic effects and can be used for clinical treatment of gastroenteritis-related gastritis, peptic ulcer and other digestive diseases.