通过动物实验,对养血止痛丸的药理和毒理进行研究,结果表明养血止痛丸对热板法、醋酸扭体法、电刺激法等引起的疼痛反应和耳肿胀,醋酸法腹部毛细血管通透性增加,琼脂法肉芽肿,蛋清性足跖肿胀等以及ADP诱导的血小板聚集均有显老的抑制作用。小鼠口服最大耐受量为30g/kg,腹腔注射醇提液LD_(50)为31.33g/kg。提示养血止痛丸是高效低毒的活血化淤,消肿止疼药物。 Through animal experiments, the pharmacology and toxicology of Yangxuezhitong pills were studied. The results showed that the blood nourishing pain pills had pain response and ear swelling caused by hot plate method, acetic acid writhing method, electrical stimulation method, and acetic acid method abdominal capillaries. Increased permeability, agar granulomas, egg white paw swelling, and ADP-induced platelet aggregation all had significant inhibitory effects. The maximum tolerated dose was 30 g/kg in mice and the LD_(50) was 31.33 g/kg. Tips Nourishing pain pills is a highly effective and low toxic blood stasis, swelling and pain medications.