用抗凝治疗视网膜血管阻塞疾患始于1937年。以往用肝素、双香豆素治疗,现在有用链激酶、尿激酶等治疗的。1963年Reid指出马来亚红口蝮蛇(Agkistrodonrhodostoma)毒中有降低血纤维蛋白原的作用。后有学者从该蛇毒中分离提纯出一种称为Arvin的酶制剂,经世界卫生组织鉴定命名为Ancrod,被认为是一种较安全有效 Treatment of retinal vascular occlusion with anticoagulation began in 1937. In the past with heparin, dicoumarol treatment, now useful streptokinase, urokinase and other treatment. In 1963 Reid pointed out that there is a fibrinogen lowering effect in the Agkistrodonrhodostoma virus. After that, some scholars extracted and purified a kind of enzyme preparation called Arvin from the snake venom and named it Ancrod by the World Health Organization, which is considered to be a safer and more effective