论文部分内容阅读
A new avirulent, heat-resistance HB92 strain of newcastle Disease Virus (NDV) was acquired from Australia V4 strain. Its complete nucleotides sequence was first determined. The entire genome of NDV HB92 consists of 15 186nucleotides (GenBank accession no. AY225110 ). It was demonstrated by sequence analysis that nucleotides homology of HB92 strain with virulent strain ZJ1 were 83.9%, and the homology compared with avirulent vaccine strain La Sota and BI were 94. 0% and 93. 5%, respectively. These results might be contributive to tbe study of the molecular mechanism of evolution of the NDV strain HB92 and to develop the engineered recombinant vaccine.