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[目的]观察祛痰清金方联合西药治疗慢性阻塞性肺疾病疗效。[方法]使用随机平行对照方法,将120例住院患者按病志号抽签法简单随机分为两组。对照组60例多索茶碱,0.2g/次,3次/d;1g头孢呋辛钠+250L 5%生理盐水,2次/d,静滴;低流量氧疗,持续吸氧,营养支持。治疗组60例祛痰清金方(栀子、瓜蒌仁各20g,桑白皮、陈皮各15g,苏子、麦冬、桔梗、甘草各6g;痰喘加射干8g,口干加芦根8g;便秘加芒硝8g),1剂/d,水煎200m L,早晚顿服;西药治疗同对照组。连续治疗14d为1疗程。观测临床症状、FEV1、FEV1/FVC、不良反应。连续治疗2疗程,判定疗效。[结果]治疗组显效27例,有效29例,无效4例,总有效率93.33%。对照组显效15例,有效30例,无效15例,总有效率75.00%。治疗组疗效优于对照组(P<0.01)。呼吸指标两组均有改善(P<0.01),治疗组改善优于对照组(P<0.01)。[结论]祛痰清金方联合西药治疗慢性阻塞性肺疾病疗效满意,无严重不良反应,值得推广。
[Objective] To observe the curative effect of expectorant Qing Jin Fang and western medicine in treating chronic obstructive pulmonary disease. [Methods] Using randomized parallel control method, 120 inpatients were randomly divided into two groups according to the random number of patients with different disease. Control group 60 cases of doxofylline, 0.2g / time, 3 times / d; 1g cefuroxime sodium + 250L 5% saline, 2 times / d, intravenous infusion; low flow oxygen therapy, continuous oxygen, nutritional support . The treatment group, 60 cases of expectorant Qingjin side (Gardenia, melon Shen 20g, Morus alba, dried tangerine peel 15g, Suzi, Ophiopogon japonicus, Campanulaceae, licorice each 6g; Constipation plus Glauber’s salt 8g), 1 / d, decoction 200m L, sooner or later Dayton clothing; western medicine treatment with the control group. Continuous treatment 14d for a course of treatment. Clinical symptoms were observed, FEV1, FEV1 / FVC, adverse reactions. Continuous treatment of 2 courses to determine the efficacy. [Results] The treatment group was markedly effective in 27 cases, effective in 29 cases, ineffective in 4 cases, the total effective rate was 93.33%. In the control group, 15 cases were markedly effective, 30 cases were effective, 15 cases were ineffective, and the total effective rate was 75.00%. The treatment group than the control group (P <0.01). The respiratory index improved in both groups (P <0.01), and the treatment group improved better than the control group (P <0.01). [Conclusion] Expectorant and Qingjin prescription combined with Western medicine in the treatment of chronic obstructive pulmonary disease has satisfactory curative effect and no serious adverse reactions, which deserves promotion.