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目的：探讨一氧化氮与脑出血的关系。方法：检测了133例脑出血患者和100例健康对照者血浆一氧化氮（P－NO）、维生素C（P－VC）、维生素E（P－VE）含量。结果：与对照组比较，患者组P-NO平均值显著升高，P－VC、P－VE平均值均显著降低；患者临床病情（NDS）和颅内血肿量均与P－NO呈正相关，而与P－VC、P－VE呈负相关。结论：脑出血患者体内自由基反应病理性加剧，氧化抗氧化平衡严重失调，宜及早抗氧化治疗。
Objective: To investigate the relationship between nitric oxide and cerebral hemorrhage. Methods: The levels of plasma nitric oxide (P-NO), vitamin C (P-VC) and vitamin E (P-VE) were measured in 133 patients with cerebral hemorrhage and 100 healthy controls. Results: Compared with the control group, the mean P-NO level and P-VC and P-VE in patients were significantly lower than those in the control group. There was a positive correlation between the severity of NDS and intracranial hematoma, But negatively correlated with P-VC and P-VE. Conclusion: In patients with intracerebral hemorrhage, the radical reaction pathological aggravate, and the balance of oxidation and anti-oxidation is seriously disordered. Antioxidant therapy should be given as soon as possible.