Flunisolide为一种新合成的类固醇药物,抗炎作用较氢化考的松强数倍,化学结构式如下。应用本药和其无效的水剂赋形剂(安慰剂)鼻内喷雾,进行双盲交叉比较。50例常年性过敏性鼻炎,男性25例,女性25例,年龄9—67岁,病程2—54年。分为两组,每组各25例。第1组应用Flunisolide 3周后应用安慰剂3周,第2 Flunisolide is a newly synthesized steroid drug with anti-inflammatory effect several times stronger than hydrocortisone, the chemical structure is as follows. The drug and its ineffective aqueous vehicle (placebo) were sprayed intranasally for double-blind crossover comparisons. 50 cases of perennial allergic rhinitis, 25 males and 25 females, aged 9-67 years, duration of 2 - 54 years. Divided into two groups, each group of 25 cases. Group 1 received Flunisolide 3 weeks after placebo for 3 weeks, group 2