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本文报道1964年起10年间所见的28例筛窦腺癌,男性24例,女性4例,年龄自37至86岁,平均为66岁。其中20例有20～55年的硬木屑粉尘接触史,主要为木器家具工人,作者强调这在病因学上有重要意义,即使在现代化的家具工业环境中,也有高浓度的粉尘,其中含有大量直径大于5μm的颗粒,主要由上呼吸道上皮捕捉,不能进入下呼吸道,所以木屑粉尘仅引起上呼吸道肿瘤的发病率增加,主要发生于筛窦。由于粉尘破坏了粘液纤毛运送作用,使其中致癌物质与中鼻甲的接触时间延长。木屑内含的致癌成分尚未明了,其中具有生物活性的成份有生物碱、皂角碱、
This article reported 28 cases of ethmoid sinus carcinoma seen in 10 years from 1964, including 24 males and 4 females, aged from 37 to 86 years, with an average of 66 years old. Twenty of them had a history of hardwood dust exposure of 20-55 years, mainly wood furniture workers. The author emphasizes that this is of great importance in the etiology. Even in the modern furniture industry environment, there are high concentrations of dust, which contains a lot of Particles larger than 5 μm in diameter are mainly captured by the upper respiratory epithelium and cannot enter the lower respiratory tract. Therefore, wood dust only causes increased incidence of upper respiratory tract tumors, which mainly occurs in the ethmoid sinuses. Due to the destruction of mucociliary transport by dust, the contact time between the carcinogen and the middle turbinate is prolonged. The carcinogenic components contained in sawdust are not yet known, and the biologically active ingredients are alkaloids, saponin,